| VERSION I: Chandler's Version
He set about cracking the mystery of Guy Robert's alternating
smell aldehydes.
He fed the Chanel 5 molecules into CAChe and set the program
to calculating electron bonds. And lo and behold under "Subject:
amazing!!!" : "Guess what!!! I suspected that aldehyde
group rotation *vibration around the Carbon-Carbon bond might
be hindered differently in the odd or even aldehydes *and*....
IT IS!!!! The [even] aldehyde rotates much more freely: you
can eyeball it in the molecular dynamics rotating in the even
(8, 10, and 12) carbon aldehydes, but remains confined to
a plane +- 20 degrees in the odd ones. Wow!! another mystery
explained." He added, "By the way, I phoned up Olivia
Giacobetti, young perfumer genius and she confirmed that the
odd and even had systematically different smells, said it
was self evident to anyone who smelled them. I'm really glad
about this one." The modeling program reported that the
odd aldehydes moved differently from the evens in a way that
changed their vibrations. The waxies had one combination of
vibrations, not identical but quite similar, the citruses
another. These combinations altered back and forth, even/odd.
(And their shapes, meanwhile, thank you very much, did *not.)
Stewart, who was never an easy scientific lay, was being
as skeptical as ever. "Quite hard to credit the story
about the odd and even chain lengths," he wrote, bulldogged.
"What *exactly* is the source of this info? I'm real
curious! How solid is the finding, do you think??"
Turin : "Which info? smells or dynamics ? Dynamics utterly
reliable, *clear* difference in the short simulations so far,
I'm running longer ones as we speak. Put it this way: the
program does not 'know' to count carbons, so even if it's
the other way round in reality, it is still a property of
some sort related to chain length. I'm damned if I know what,
though, I can't *see* it in things like partial charges, bond
orders, etc."
No, no, Stewart had meant the smells: "Did Olivia describe
the difference in smells to you??? Have you smelled them yet??"
Turin: "She said that it was citrus vs wax respectively
for even and odd, just like Guy Robert had."
But again Stewart: "OK, here's my question: *what* exactly
does the modeling program spit out?? Are you doing this by
eyeballing a simulation, or does it print out some sort of
values?? Extremely curious about this."
"So far, eyeballing," Turin replied. "Using
standard parameters in augmented MM2, a piece of software
inside CAChe that takes into account everything xcept the
moons of Saturn."
Stewart "Roger on citrus vs wax, that sounds consistent.
Aldrich sell these guys????" Stewart meant C6, C7, C8,
C9, C10, C11, and C12.
"Yup," Turin wrote. "I'm ordering them today
from Aldrich." He added "Guy Robert warned me about
two things: first of all, the things age ungracefully, and
secondly the perfume suppliers actually supply impure ingredients
*on purpose* to personalise their supply and make it smell
better !! (Aldrich does not, to my knowledge)."
(Stewart wondered if he was being maybe a bit too bulldogged
a critic. "Tell me if I'm missing the boat here..."
he emailed doubtfully.)
"No, no!!" Turin replied quickly, "all good
and useful comments.")
The aldehyde finding was only getting stronger. Mopac and
CAChe were whispering that the odd aldehydes danced differently
from the evens in a way that affected their vibrations. The
waxies had one vibration; the citrusies had another.
He set about cracking the mystery of Guy Robert's alternating
smell aldehydes.
He fed the Chanel 5 molecules into CAChe and set the program
to calculating electron bonds. And lo and behold... "Amazing!!!"
he emailed Stewart. Just as he had suspected, it looked like
the aldehyde group rotation *vibration was different in the
odd or even aldehydes. The evens rotated much more freely.
He could even eyeball it, the molecular vibes huge in 8, 10,
and 12 but minimal in 9, 11, and 13. "Wow!" he exclaimed.
"another mystery explained." Oh, he added, he'd
phoned up Olivia Giacobetti, a young perfumer he considered
a genius, and she'd confirmed that the odd and even aldehydes
had systematically different smells. He was thrilled. The
waxies had basically one vibration, the citruses another.
(And their shapes, meanwhile, thank you very much, did *not.)
Stewart, who was never an easy scientific lay, was being
as skeptical as ever, what was the source of the information,
how solid was it really, etc. Which information, asked Turin,
smells or dynamics? The dynamics utterly reliable, in his
view, a clear difference in the short simulations so far,
and he was running longer ones as they spoke. Put it this
way, he said, the program didn't "know" to count
carbons, so even if was the other way round in reality, it
was still a property related to chain length.
No, no, Stewart had meant the smells. Had Olivia described
the difference? Had *Turin smelled the difference?
Turin replied that Giacobetti had described their smells
exactly as Guy Robert had, that they were citrus vs wax respectively
for even and odd, but Stewart then simply attacked from another
angle, asked what *exactly the modeling program was spitting
out. Was Turin eyeballing it or was the thing printing out
specific number values for him? He was eyeballing it so far,
said Turin. Using a program that took into account everything
except the moons of Saturn. He was ordering the molecules
from Aldrich that day (slightly weird piece of information
from Guy Robert, apparently the perfume suppliers actually
supplied impure ingredients *on *purpose to personalize their
products and make them smell better; Aldrich, to his knowledge,
did not)."
The aldehyde finding was only getting stronger. Mopac and
CAChe were whispering that the odd aldehydes danced differently
from the evens in a way that affected their vibrations. The
waxies had one vibration; the citrusies had another.
|